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Similarly, branched-chain amino acids, such as leucine, isoleucine, and valine, are catabolized in skeletal muscle to produce acetyl-CoA and succinyl-CoA, which enter the TCA cycle and contribute to ATP production

A total of 214 patients were randomized in a 1:1:1 ratio to either 3 mg or 6 mg oral once daily FXR314, or placebo

It also provides an indication of the viscous load likely to be encountered during mixing