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*Correspondence: Dan Zhou, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

J Clin Neurosci 17(6):717721

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In fact, the metabolic changes in glucose, lipids, and amino acids provide the cancer cells with the energy and substances needed for biosynthesis and the maintenance of biological functions ( de novo cysteine synthesis from methionine which is recognized as an additional mechanism for maintaining cysteine pools in the tumor microenvironment ( N -methyltransferase may contribute to cysteine biosynthesis and promote cancer cell survival in cysteine-limited microenvironment, which has been demonstrated to support tumor growth in vivo ( Post-translational modifications targeting cysteine of protein in cancer PTMs is a biochemical modification occurring to one or more amino acids on a protein during or after protein translation

Additionally, the procedure can be painful, deterring many from choosing this method