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Description

SARM, selective androgen receptor modulator

These differences were statistically significant, showing that TE had a dose-dependent effect on weight loss

Importantly, preclinical studies showed that weight reduction occurred particularly in abdominal adipose tissue, the visceral fat depot most strongly associated with metabolic health risks

One way of assessing drug synergy consists of combining drugs at half of their IC50 concentration for a two-drug combination, and one-third of their IC50 concentration for a three-drug combination (39, 70)