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ALKBH5-mediated m(6)A demethylation of FOXM1 mRNA promotes progression of uveal melanoma

124 SloanJ

By using mice deficient in glutamate-cysteine ligase (GCL) in keratinocytes, the authors found that GSH deficiency results in more DNA damage and cell death, suggesting a crucial role for the antioxidant capacity in skin integrity maintenance [93]