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John DiBella Published: November 3, 2025 Fact-checked by Dr

Prevents Folate Deficiency: Folic acid helps to promote healthy cell development and prevents folate deficiency-related anaemia

Severity of Deficiency : Severe deficiencies often require injections to restore B-12 levels quickly

A study using antibiotic treatment to deplete butyrate-producing microbes revealed that this type of dysbiosis supports Enterobacteriaceae expansion and inflammation through suppression of the peroxisome proliferator-activated receptor gamma (PPAR-) homeostatic signaling pathway [38]

These guidelines synthesize evidence from multiple trials and provide recommendations on patient selection, dosing, monitoring, and combination therapy strategies