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"Like fasting," it said, "colonic cleansing carries a risk of dehydration, electrolyte imbalance, impaired bowel function, and disruption of intestinal flora." Edzard Ernst, professor of complementary medicine at Exeter University, called the concept of detoxing both a scandal and "criminal exploitation of the gullible man" in a 2014 interview with the Guardian

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PMID:12566075

For neurological applications, the evidence is more preliminary and the extrapolation from rodent to human more uncertain

untreated sham 218 22 g/g