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Description

J Gastrointest

Pan-cancer analysis of whole genomes

10:e725

10.1016/j.ejca.2018.03.012 Summary Keywords mTORC1, mitochondria, mitochondrial functions, cancer, therapy Citation de la Cruz Lpez KG, Toledo Guzmn ME, Snchez EO and Garca Carranc A (2019) mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in Cancer

We also observed decreased RAD51 and BRCA1 recruitment to DSBs in cells treated with the IDH1 inhibitor, which was rescued by KG, l-carnitine and acetylcarnitine (Fig