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Which makes it surprising when you hear that B12 deficiency is relatively common

Using the bioactive form adds a marginal advantage

Site selection influences both comfort and absorption

This depends on the severity of your deficiency, but many people start with a short loading course followed by maintenance injections every few months

Interestingly, B12 did not affect the intracellular protein levels of IL-1B in the cultures of the SEV group, and, regardless of the treatment, the intracellular protein levels of IL-1B were very low, close to or below the detection limit of the method ( Figure 3F )