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Melatonin is also responsible for the stimulation of the enzyme sirtuin 3 (SIRT3), which causes the deacetylation and activation of SOD2 [12,47]

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Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus

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Krafts team fingered the rate-limiting BH4-maker GCH1 as a potent ferroptosis brake through a CRISPR/dCas9 overexpression screen

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Moreover, they documented reduced hippocampal plasticity genesalongside a change in the rodents behavior (Venkidesh et al., 2023)

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doi: 10.3390/ijms23105367 364 YeZ.-C.WyethM

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