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Yellow/blue or orange/blue contrast is the optimal stimulus for these neurons in the eye that wake up the brain and the rest of the body

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Because NGF induces an antioxidant response via TrkA/Akt or MAPK signaling pathway, these data support our previous finding that increased levels of GSH in the brain are associated with ERK2 activation ( Our findings suggest that systemic NGF helps to maintain redox homeostasis, which would explain why NGF and TrkA levels are increased in both the plasma and brain during the systemic oxidative stress generated by physical activity (Ang et al., 2003

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VEGF plays a pivotal role in angiogenesis, the formation of new blood vessels, which is critical for delivering oxygen and nutrients to healing tissues while eliminating metabolic waste