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Those dealing with fatigue or recovering from low levels often find B12 beneficial

The table lists the biomarkers followed by four columns with relevant nonclinical information about the discovery process, and the last three columns have relevant information about the current status of clinical validation of the potential protein biomarker of liver injury

B12 deficiency causes real physical fatigue, the kind that no amount of willpower pushes through

Malliaras P, Barton CJ, Reeves ND, Langberg H

10.1038/31269 Summary Keywords cuprizone mouse model, remyelination, demyelination, growth factors, microglia, astrocytes Citation Gudi V, Gingele S, Skripuletz T and Stangel M (2014) Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned