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Haack M

10.1038/nature09572 67 HaatajaL.ArunagiriA.HassanA.ReganK.TsaiB.DhayalanB.et al (2021)

doi: 10.1016/j.bbrc.2020.12.048 53 Lammerts van BuerenJJakobsDKaldenhovenNRozaMHiddinghSMeestersJet al

It has been suggested, based upon a recent network meta-analysis that adjusted for differences in maintenance trial design, that upadacitinib is numerically superior to other therapies in induction and maintenance of clinical remission and endoscopic improvement

Alternatively, covalent coupling of surface ligands is a crosslinking mechanism that requires a highly compact ligand layer with terminal functional groups