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Seto, E

Maintaining compliance with national safety recommendations protects patient health daily

Drug development has a well-documented failure rate: roughly 90% of compounds that show promise in animal models fail in human trials

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Marked elevations in liver function test results (e.g., AST [SGOT] and ALT [SGPT]), occurred on 2 occasions following administration of high doses (total doses: 106 and 250 g over 3-4 days) of acetylcysteine rectally and via nasogastric tube in a 3-year-old boy with cystic fibrosis