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Both men and women with prolactinoma can present with persistent impaired bone mineral density (BMD), despite long-term control of hyperprolactinemia and hypogonadism (33).Therefore, it has been suggested that all patients with prolactinoma should be submitted to a bone health evaluation at diagnosis with DXA scan, morphometric vertebral fracture (VF) assessment, and 25 (OH) vitamin D levels

All of these receptors have tyrosine kinase activity, hence are natural and potent activators of the Akt pathway [9]

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176 The combination of cisplatin and 6-AN optimizes the clinical dose and minimized the side effects