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This is an important safety distinction

A quick reference explanation of the tests mentioned below

NHS B12 therapy is evidence-based for documented deficiency, using hydroxocobalamin 1mg intramuscularly with standardised protocols

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[2] Use of estradiol cypionate injection is contraindicated in individuals with undiagnosed abnormal vaginal bleeding, known or suspected breast cancer or other estrogen-dependent neoplasia, active or prior venous thromboembolism, recent arterial thrombo-occlusive disease such as stroke or myocardial infarction, severe hepatic impairment, a history of hypersensitivity to estradiol or any excipients, and in those who are or may become pregnant