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For example, opioids decrease pulmonary perfusion via hypoxia-induced pulmonary vasoconstriction 143 , and by direct pulmonary vasoconstriction 144,145 by mechanisms including centrally-mediated activation of sympathetic nerve activity to the lungs 146 , and induction of histamine release in the lungs 144,147

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elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway

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S., Harkness, T., Fu, X., Stone, J