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Neither cagrilintide nor retatrutide is FDA-approved for the use described here as of June 2026

Acknowledgements The authors are grateful to U

Mar 2018;16(1):10-20

While immune and neuroinflammatory responses are protective against infection and injury, excessive activity in these pathways can damage normal tissues, leading to inflammatory injury of dopaminergic neurons and driving PD progression ( In MPTP-induced PD mouse models, astragaloside IV (AS-IV), the primary active component of Astragalus membranaceus (Fisch.), administered at doses of 1.5, 3, and 6 mg/kg for 10 days, demonstrated dose-dependent improvements in motor dysfunction

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