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References: Vitamin B 12 CPhA Monograph

Researchers are also investigating new targets such as histamine receptors, VEGF, matrix-metalloproteinase, and sirtuin receptors for potential anti-obesity drugs

PMC 8140678

Vitamin B-12 can help increase lipid metabolism (burn fat) in your body by increasing the effects of exercise and supplements you take

Since fat builds up in the liver, it only decreases the bodys metabolic rate, making it impossible to lose weight even with a balanced diet and exercise