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A single systemic injection in EAE mice induced apoptosis of pathogenic T cells within lymphoid organs, promoted macrophagederived TGF secretion, and expanded antigenspecific Tregs approximately 5-fold

To generate the endogenous dTAG-inducible degradation system for CTPS1, sgRNA targeting the start codon region and pUC19 plasmid were co-transfected into the HeLa cells or H1.4-KO HeLa cells expressing wild-type or mutant FlagH1.4

Administration for intermittent or continuous prolonged periods, including overnight, may be desirable

887 D-mannose also protects cartilage by inhibiting HIF-2 and reducing the sensitivity of chondrocytes to ferroptosis