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120 In myeloid cell-specific SIRT1 knockout mice, lipid toxicity or LPS stimulation induced more severe hepatic inflammation, elevated pro-inflammatory cytokine levels, and enhanced M1 macrophage polarization, highlighting the critical role of SIRT1 in preserving immune balance

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By inhibiting the IL-6R-JAK/STAT signaling pathway, triptolide impedes tumor cell proliferation, survival, and the inflammatory response, which are critical for cancer progression [980]

[8] [19] However, EFA deficiency in humans was first described by Arild Hansen only in 1958, in infants fed a milk-based formula lacking them

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