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Further, to understand if apoptosis contributed to the decline in CX 3 CR1 CCR2 tissue-resident macrophage numbers in obese mice, we measured annexin V, a late apoptosis marker, and caspase 3, an early apoptosis marker, in this macrophage population

LDLr -/- mice liver homogenates

doi: 10.3389/fphar.2017.00608 36 JaroszAPWeiWGauldJWAuldJOzcanFAslanMet al

Principal Possible mechanisms of action of BPC-157

The TCM herbal monomer Danshinone IIA (Tan IIA) can alleviate kidney damage in db/db mice, possibly by inhibiting cell pyroptosis through the regulation of NLRP3 and thioredoxin-interacting protein (Txnip) expression, thus delaying the progression of diabetic kidney disease (DKD) (Wu et al., 2023a)