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For example, OBX-115 expresses membrane-bound human IL-15 under pharmacological control to provide cell-intrinsic survival and proliferation signals and potentially reduce the need for exogenous IL-2 [109, 111]

Oral versus intravenous amino acids for kidney protection during peptide receptor radionuclide therapy

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While IL-6 signals through the IL-6R and gp130 to activate downstream pathways, vIL-6 signals through gp130 homodimers [108]

In both compartments, acetate is converted into acetyl-CoA via thioesterification, consuming energy equivalent to two terminal phosphate bonds from ATP 254,255