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Endocr Rev (1995) 16(1):334

They are also known to cause hepatic dysfunction, which is thought to be secondary to inhibition of glutathione synthesis and oxidative stress pathways, resulting in cell lysis

Herein, we systemically elaborate on the regulatory mechanisms of ferroptosis in the following aspects

Copper Transport and Bioavailability Copper is an essential cofactor for lysyl oxidase, superoxide dismutase, and several other enzymes critical to connective-tissue assembly and redox balance