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EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer

It targets GLP-1, GIP, and glucagon receptors, showing promising results for weight loss, blood sugar control, and overall metabolic health

The balance between reactive oxygen species (ROS) and antioxidants plays a crucial role in cancer chemoresistance, influencing drug efflux, epithelial-to-Mesenchymal Transition (EMT), pro-survival signalling, and apoptosis inhibition [76, 77]