function of glutathione as chaperone Chaperones—A New Class Potential Therapeutic Targets in Alzheimer's Disease Frontiers | Iron-tracking strategies: Chaperones

In endothelial cells (ECs), copper overload disrupts mitochondrial dynamics, increases fission and ROS production, and ultimately leads to cell death [34] In cardiomyocytes, copper promotes hypertrophy and inflammation [35], disrupts fatty acid and lipid metabolism, upregulates autophagy-associated proteins and genes, and impedes calcium ion uptake by the sarcoplasmic reticulum, thereby inhibiting myocardial contractility [36]

SW: Data curation, Formal analysis, Supervision, Visualization, Writing review & editing

Results: While clinical parameters alone showed limited predictive accuracy (40% accuracy, AUC 0.62), radiomics features demonstrated modest performance (55% accuracy, AUC 0.79)

Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury

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