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The 2021 fifth edition of the WHO Classification of CNS Tumors categorizes MBs into four distinct molecular subgroups: WNT-activated, SHH-activated with TP53 wild type, SHH-activated with TP53 mutation, and non-WNT/non-SHH (formerly classified as groups 3 and 4 (50, 5860)

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Duration of use typically ranges from 4-8 weeks for acute conditions to 6-8 weeks or longer for chronic plantar fasciitis

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