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(There are many genetic predispositions associated with fatigue conditions, such as MTHFR, MTRR, MTR, etc

In another clinical study conducted on 565 patients with tuberculosis, there was no significant difference between patients receiving silibinin and the control group after 8 weeks of treatment, while fewer patients in the treatment group had symptoms of liver damage such as anorexia and nausea compared to the control group [145]

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These disorders augment the circulating level of Homocysteine with the development of hyperhomocysteinemia, which may involve the pathogenesis of PD