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Selective -Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinsons Disease

HiguchiTOshiroHMiyakeKSugisawaNHanQTanYet al

It has been shown that, following type IV pili-mediated contact, the pilE gene encoding the major pilin and the genes for capsule synthesis are downregulated, and this is thought to allow for more intimate adhesion through other outer membrane adhesins