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513,514 Astrocytes from FMR1 knockout mouse model of fragile X syndrome were characterised by an enhanced secretion pf interleukin-6 and tenascin C, as well as by increased purinergic signalling

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The foundational trial is Q-SYMBIO, a randomised, double-blind, placebo-controlled multicentre study across 420 patients with moderate-to-severe chronic heart failure