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Inhibition of HIF-1/EP4 axis by hyaluronate-trimethyl chitosan-SPION nanoparticles markedly suppresses the growth and development of cancer cells

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In MCF-7 cells, TGF--induced GLS1 expression is mediated by the transcription factor Dlx-2, leading to enhanced glutamine metabolism that contributes to EMT (Lee et al., 2016)