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A combination treatment is usually prescribed to achieve optimal patient outcomes in the real-world practice [103]

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Specifically, these CAR-T cells feature the truncated cytoplasmic domain of the IL-2 receptor beta chain (IL-2R), which activates the JAK-STAT signaling pathway, promoting cell proliferation and preventing terminal differentiation in vitro ( Figure 2A

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Citations Citations to this article as recorded by Trends and Impacts of Advanced Therapy on Chronic Opioid Use in Asian Patients with Inflammatory Bowel Disease Yu Kyung Jun, Eunjeong Ji, Yonghoon Choi, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, Hyuk Yoon Inflammatory Bowel Diseases.2026