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Jung WK, Choi I, Oh S, Park SG, Seo SK, Lee SW, et al

Der erhaltene Niederschlag wurde mittels Filtration isoliert, einmal mit frischem Aceton gewaschen und unter reduziertem Druck getrocknet, um 965 mg der Verbindung der Formel 3f als ein gelbes Pulver zu ergeben.1.0 g of calcium salt of the formula 3i was added to 15 ml of a 0.133 M solution of the oxalic acid salt of tert-butylamine and the mixture was stirred at a temperature of + 4 C

Warnings : cocaine toxicity can cause patients to become aggressive, & combative the role of lidocaine in treating ventricular arrhythmias is unclear (there are concerns with it's use due to the fact that it is a Na channel blocker - like cocaine, and may worsen cardiac conduction disturbances or induce seizures) non-selective beta blockers should be avoided (due to concern about creating unopposed alpha-adrenergic mediated coronary vasoconstriction in the presence of elevated catecholamines, with blockade of beta-2 receptors) in the absence of serious toxic reactions, the (non-lethal) acute effects of cocaine are generally short-lived due to its short half life (~50 mins) although this may be prolonged 2-3 fold if alcohol is co-ingested (due to the formation of cocaethylene , which has a longer half life) References: Olson KR (2007): Poisoning & Drug Overdose

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