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Many larger health claims regarding longevity, organ regeneration and disease treatment are yet to undergo large scale human clinical trials

If dietary protein intake is insufficient, particularly glycine and proline which are collagens primary building blocks, the anabolic signaling has limited raw material to work with

Of course, using injectables requires adherence to strict protocols

The broader picture is one in which MOTS-c addresses a gap that many other longevity interventions leave unfilled: the mitochondrial signaling decline that is simultaneously a cause and consequence of metabolic aging