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Since cortisol is a wakefulness hormone, a spike in the evening could certainly disrupt sleep patterns

10.3389/fphys.2018.00527 119 LiZ.XuH.LiJ.PengR.FanQ.DengQ

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Other chemicals known to induce ferroptosis, including RSL3 and buthionine sulfoximine (BSO), did not increase the expression of XBP1s or ATF4 (Supplementary Fig