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10.1073/pnas.93.25.14428 Proc

The involvement of oxidative stress in the breakdown of immune tolerance is another crucial mechanism in the pathogenesis of autoimmune diseases

Inhibition of GCS It is well known [27, 41] that GSH is a competitive inhibitor against glutamate of GCS, the enzyme that catalyzes the synthesis of glutamyl-cysteine

Furthermore, the ability of S-acetyl L-glutathione to cross cell membranes more easily than regular glutathione is a crucial factor in its potential increased effectiveness

A diet low in iron-rich foods can contribute to this, or the body can also have problems absorbing iron despite eating a healthy diet