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Moreover, cystine partially restored infection-induced intestinal permeability to basal (pre-infection) levels, suggesting a beneficial effect of cystine on gut barrier function

Additionally, 4-aminoquinolines could act as TLR agonists or antagonists, which could favor macrophage activation and activate the innate immune macrophage system, which emerges as an extra defense mechanism to attack parasites within the macrophage

Kang, Y

doi: 10.1016/j.jdermsci.2015.09.003 38

FIGURE 1 Ferroptosis appears to require the presence of specific highly oxidisable phosphatidylethanolamine phospholipids containing the polyunsaturated fatty acids (PUFAs) arachidonic acid and adrenic acid