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3.1.3 Analysis of circulating tumor cells in patients with metastatic breast cancer Circulating tumor cells (CTCs) and CTC clusters play pivotal roles in metastatic cascade through their detachment from primary tumors, survival in circulation, and targeted colonization

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In combination with aspirin, triptolide further blocks NF- B activation in cancer cells through distinct mechanisms involving p53 and ERK1/2, contributing to a reduction in cancer incidence [971, 972]