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Many studies, both in vitro and in vivo reported melatonin as a very good scavenger of free radicals, especially in cancers, neurodegenerative disorders, and psychiatric diagnosis

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Isenovic (2015) Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases, Critical Reviews in Clinical Laboratory Sciences , 52:2, 70-85, Baldelli, S., Ciccarone, F., Limongi, D., Checconi, P., Palamara, A

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Animal experiment also documented correlations of serum UA levels with lower striatal dopamine levels, tyrosine hydroxylase-positive neuronal death in the SN pars compacta, and the degree of oxidative stress in the midbrain