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Research has shown that an injection therapy program involving this hormone, when used in conjunction with a strict diet, can be an effective way to reach weight loss goals

Its effects on energy metabolism and related biology are mediated through specific enzymatic and metabolic pathways

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Human studies have shown that PYY delays gastric emptying and promotes satiety (165), while short-term intravenous administration of PYY3-36 , at doses generating physiologic postprandial blood excursions, was shown to decrease calorie intake by approximately 30% in lean and obese subjects, without causing nausea, affecting food palatability, or altering fluid intake, nor was it followed by compensatory hyperphagia (166)

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