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Scheijen, J., Clevers, E., Engelen, L., Dagnelie, P

Previous work suggested that only about 50% of all PD patients have a distribution of LBP in the brain that is entirely consistent with the Braak staging model, a prerequisite for the assumption that iLBD is a precursor for SNc pathology in PD [29, 214, 215], and about half of PD cases do not seem to show a caudo-rostral spread of LBP throughout the brain [216]

Efficacy and safety of long-term treatment with the dual 5 alpha-reductase inhibitor dutasteride in men with symptomatic benign prostatic hyperplasia

Biochemical treatment targets may be helpful (Table 10)

Figure 1 3 Mechanism of RIC treatment As previously delineated, the therapeutic efficacy of RIC is highly dependent on its execution protocol, which is broadly categorized into RIPreC, RIPerC, RIPostC, and CRIC