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the sealed serum vial pushes its payload through those channels during the brief 2-to-24-hour window before the channels close, delivering each molecule to the cellular layer it acts on rather than depositing it on top of an intact skin barrier where most of it would have done nothing

At this concentration, a 2.5 mg dose equals 0.50 mL (50 units on an insulin syringe)

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(3) Co-treatment of natural compounds and other drugs should be studied for improved treatment