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Psychiatric symptoms were evaluated using the 18-item Brief Psychotic Rating Scale (BPRS)[12] and the Clinical Global Impression-Severity (CGI-S)[13] scale at baseline, and one, two, and three months, and the Global Assessment of Functioning (GAF) scale at baseline and three months

Therefore, the dose requirement for these types of drugs may be lower in many older patients [34]

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Elevated circulating TMAO levels resulted in endothelial dysfunction in elderly rats, which was reversed by DMB treatment for 8 weeks (Li et al., 2017)

TCM can modulate lipid metabolism through altering levels of TMAO