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There is also a critical need for well-designed long-term safety studies addressing the potential side effects of chronic polyphenol supplementation, as current data are mainly limited to short-term animal experiments or isolated compounds, and results from these do not always translate directly to humans (121)

ChamQ Universal SYBR qPCR Master Mix (Q711 Vazyme) was mixed with the cDNA and gene-specific primers, and qPCR was performed according to the manufacturers protocol

The Mann Whitney test (two-tailed) was used to determine the significance between two groups

Jimenez-Shahed:There are maybe individuals who understand that these types of involuntary movements might be related to the fact that the patient is being treated for a psychiatric condition