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Treatment with a CB2R agonist increased the proliferation of B lymphocytes, a phenomenon that was blocked by a CB2R antagonist (95)

Redrobe JP, Elster L, Frederiksen K, Bundgaard C, de Jong IE, Smith GP, et al

Get the escalation wrong and you either lose efficacy or gain side effects you did not need

Regarding to the secondary products present in the drug, it is evidence that antioxidants reduce the platelet activity through stimulation of prostacyclin synthesis and scavenging the synthesis-inhibiting peroxides