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This review provides an overview of current knowledge regarding the etiology, inducements, pathophysiology, and available treatments for migraine, with a focus on the clinical and experimental evidence of neurogenic inflammation and oxidative stress in migraine

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Kynurenic acid is thought to have protective effects on mitochondrial respiration, whereas accumulation of quinolinic acid is associated with mitochondrial dysfunction (71)

However, a functional role of mitochondrial disease in ASD phenotype has been proposed by some researchers [74]