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Adecatumumab, which has a moderate affinity to EpCAM, can target tumor cells with high EPCAM expression and reduce aggression and metastasis in patients with fewer side effects [194]

Notably, tyrosine hydroxylase in the striatum is activated by BDNF, which maintains the dopaminergic neurons in the SNpc (Cao et al., 2022

Briefly, cells were sequentially treated with the medium containing 25 M of CldU (Sigma-Aldrich, C6891) and then 250 M of IdU (Sigma-Aldrich, I7125) for 20 min