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This coordinated collaboration will shift cancer management from reactive intervention to proactive control, a paradigm shift in treatment strategies.``````` Statements Author contributions XZ: Conceptualization, Formal Analysis, Investigation, Methodology, Validation, Visualization, Writing original draft, Writing review and editing

1 Introduction The growing global burden of cancer necessitates innovative strategies that span prevention, treatment sensitization, and mitigation of therapy-related toxicity ( Epidemiological studies have consistently linked the consumption of glucoraphanin-rich cruciferous vegetables with a reduced risk of several cancers, including those of the prostate, lung, and colorectum ( The efficacy of SFN is intrinsically linked to the biosynthesis of its precursor, glucoraphanin, in the plant itself