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JAMA 323 , 15651573 (2020)

This combination runs for 6 to 8 weeks minimum

The thioredoxin system acts as a scavenger for ROS, while SOD uses Cu, Zn, and Mn as cofactors to break down superoxide anions into H 2 O 2 and O 2

The morphological responses can be assessed by light and electron microscopy and immunohistochemistry and should be interpreted in conjunction with clinical pathology alterations (Ennulat et al