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doi: 10.1111/jcmm.17275 84 SunLWangHYuSZhangLJiangJZhouQ

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Further research has demonstrated that this dysregulation of the negative feedback mechanism plays a vital role in PTSD, potentially being a key factor causing the persistence of chronic stress states (Sriram et al., 2012)

Am J Epidemiol 139(12):11801189

Homocysteine levels were also correlated with obesity, smoking, defects in the MTHFR gene, and deficiencies of vitamin B12 and folate.23 Evidence from clinical trials for the beneficial role of a regimen of supplemental folate, vitamin B6, and vitamin B12 on CVD risk is lacking