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These cells subsequently induce the production of IL-22, which regulates the release of antimicrobial peptides and enhances their expression in the gut epithelium, thereby reducing pathogen infectivity by sequestering metal ions [52]

In September, both NPRA and Singapores Health Sciences Authority issued advisories against several products, including traditional Chinese pimple patch Chang-Sze-Long Badu Gao, which contains mercury, as well as JC Beauty Culture Radiance Renewal Serum and The Perfect Derma Cream, which were found to contain hydroquinone, tretinoin and miconazole, an antifungal medicine not approved for cosmetic use

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The highest priority attribute was surveillance benefits (42.9%